# How to Build a Voice AI Agent with OpenAI's GPT-Live, Twilio Agent Connect, and Python

DevFeed: [How to Build a Voice AI Agent with OpenAI's GPT-Live, Twilio Agent Connect, and Python](<https://devfeed.tech/articles/how-to-build-a-voice-ai-agent-with-openai-s-gpt-live-twilio-agent-connect-and-python-16092.md>)

Original publisher: [Read original article](<https://www.twilio.com/en-us/blog/developers/tutorials/integrations/tac-gpt-live-voice-ai-agent-python>)

Author: Xinghao Huang

Published: 2026-09-10T00:00:00Z

Content type: tutorial

Language: en

Sources: [Twilio Blog](<https://devfeed.tech/sources/twilio-blog.md>)

Topics: [voice ai](<https://devfeed.tech/topics/voice-ai.md>), [AI Agent](<https://devfeed.tech/topics/ai-agent.md>), [Python](<https://devfeed.tech/topics/python.md>), [OpenAI](<https://devfeed.tech/topics/openai.md>), [SDKs](<https://devfeed.tech/topics/sdks.md>), [API](<https://devfeed.tech/topics/api.md>)

Tags: [ai](<https://devfeed.tech/tags/ai.md>), [ai-agent](<https://devfeed.tech/tags/ai-agent.md>), [and-best-practices](<https://devfeed.tech/tags/and-best-practices.md>), [api](<https://devfeed.tech/tags/api.md>), [backend](<https://devfeed.tech/tags/backend.md>), [code](<https://devfeed.tech/tags/code.md>), [developer-insights](<https://devfeed.tech/tags/developer-insights.md>), [how-to](<https://devfeed.tech/tags/how-to.md>), [openai](<https://devfeed.tech/tags/openai.md>), [python](<https://devfeed.tech/tags/python.md>), [sdk](<https://devfeed.tech/tags/sdk.md>), [tutorials](<https://devfeed.tech/tags/tutorials.md>), [voice-ai](<https://devfeed.tech/tags/voice-ai.md>)

## AI overview

A tutorial for building inbound and outbound phone voice AI agents with Python, Twilio Agent Connect, and OpenAI's GPT-Live. It covers tool calls, proactive greetings, per-call customization, and configuration for Twilio Media Streams.

## Source excerpt

Build inbound and outbound voice AI assistants that can handle tool calls using Python, Twilio Agent Connect, and OpenAI's GPT-Live.